• Acute Effects of Vitamin D 3 Supplementation on Muscle Strength in Judoka Athletes: A Randomized Placebo-Controlled, Double-Blind Trial 

      Wyon M.A., Wolman R., Nevill A.M., Cloak R., Metsios G.S., Gould D., Ingham A., Koutedakis Y. (2016)
      Objective: Indoor athletes have been shown to be prone to vitamin D 3 deficiency. The aim of the study was to examine the acute effects of vitamin D supplementation on muscle function using isokinetic dynamometry. Design: ...
    • Administration of low-molecular-weight heparin in patients with two or more unsuccessful IVF/ICSI cycles: a multicenter cohort study 

      Siristatidis C., Dafopoulos K., Salamalekis G., Galazios G., Christoforidis N., Moustakarias T., Koutlaki N., Bouschanetzis C., Loutradis D., Drakakis P. (2018)
      To compare the effects of the administration of low-molecular-weight heparin (LMWH) in subfertile patients with two or more unsuccessful IVF/ICSI cycles. In this six-center two-arm retrospective cohort study, the study ...
    • Administration of prednisolone and low molecular weight heparin in patients with repeated implantation failures: a cohort study 

      Siristatidis C., Dafopoulos K., El-Khayat W., Salamalekis G., Anifandis G., Vrantza T., Elsadek M., Papantoniou N. (2018)
      Conflicting results exist for low molecular weight heparin (LMWH) and prednisolone when tested as separate adjuncts for the improvement of the clinical outcomes in patients with repeated implantation failures (RIF) undergoing ...
    • Adrenal, thyroid and gonadal axes are affected at high altitude 

      Wolff M.V., Nakas C.T., Tobler M., Merz T.M., Hilty M.P., Veldhuis J.D., Huber A.R., Hefti J.P. (2018)
      Humans cannot live at very high altitude for reasons, which are not completely understood. Since these reasons are not restricted to cardiorespiratory changes alone, changes in the endocrine system might also be involved. ...
    • Age, Body Mass Index, and Daytime and Nocturnal Hypoxia as Predictors of Hypertension in Patients With Obstructive Sleep Apnea 

      Natsios G., Pastaka C., Vavougios G., Zarogiannis S.G., Tsolaki V., Dimoulis A., Seitanidis G., Gourgoulianis K.I. (2016)
      A growing body of evidence links obstructive sleep apnea (OSA) with hypertension. The authors performed a retrospective cohort study using the University Hospital of Larissa Sleep Apnea Database (1501 patients) to determine ...
    • Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study 

      Lipnicki D.M., Crawford J.D., Dutta R., Thalamuthu A., Kochan N.A., Andrews G., Lima-Costa M.F., Castro-Costa E., Brayne C., Matthews F.E., Stephan B.C.M., Lipton R.B., Katz M.J., Ritchie K., Scali J., Ancelin M.-L., Scarmeas N., Yannakoulia M., Dardiotis E., Lam L.C.W., Wong C.H.Y., Fung A.W.T., Guaita A., Vaccaro R., Davin A., Kim K.W., Han J.W., Kim T.H., Anstey K.J., Cherbuin N., Butterworth P., Scazufca M., Kumagai S., Chen S., Narazaki K., Ng T.P., Gao Q., Reppermund S., Brodaty H., Lobo A., Lopez-Anton R., Santabárbara J., Sachdev P.S., Cohort Studies of Memory in an International Consortium (COSMIC) (2017)
      Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related ...
    • aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis 

      Fan R., Papatheodoridis G., Sun J., Innes H., Toyoda H., Xie Q., Mo S., Sypsa V., Guha I.N., Kumada T., Niu J., Dalekos G., Yasuda S., Barnes E., Lian J., Suri V., Idilman R., Barclay S.T., Dou X., Berg T., Hayes P.C., Flaherty J.F., Zhou Y., Zhang Z., Buti M., Hutchinson S.J., Guo Y., Calleja J.L., Lin L., Zhao L., Chen Y., Janssen H.L.A., Zhu C., Shi L., Tang X., Gaggar A., Wei L., Jia J., Irving W.L., Johnson P.J., Lampertico P., Hou J. (2020)
      Background & Aims: Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a global universal HCC risk score to predict the ...
    • Amino acid signatures in the HLA class II peptide-binding region associated with protection/susceptibility to the severe West Nile Virus disease 

      Sarri C.A., Papadopoulos G.E., Papa A., Tsakris A., Pervanidou D., Baka A., Politis C., Billinis C., Hadjichristodoulou C., Mamuris Z. (2018)
      The MHC class II region in humans is highly polymorphic. Each MHC molecule is formed by an α and a β chain, produced by different genes, creating an antigen-binding groove. In the groove there are several pockets into which ...
    • AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders 

      Salpietro V., Dixon C.L., Guo H., Bello O.D., Vandrovcova J., Efthymiou S., Maroofian R., Heimer G., Burglen L., Valence S., Torti E., Hacke M., Rankin J., Tariq H., Colin E., Procaccio V., Striano P., Mankad K., Lieb A., Chen S., Pisani L., Bettencourt C., Männikkö R., Manole A., Brusco A., Grosso E., Ferrero G.B., Armstrong-Moron J., Gueden S., Bar-Yosef O., Tzadok M., Monaghan K.G., Santiago-Sim T., Person R.E., Cho M.T., Willaert R., Yoo Y., Chae J.-H., Quan Y., Wu H., Wang T., Bernier R.A., Xia K., Blesson A., Jain M., Motazacker M.M., Jaeger B., Schneider A.L., Boysen K., Muir A.M., Myers C.T., Gavrilova R.H., Gunderson L., Schultz-Rogers L., Klee E.W., Dyment D., Osmond M., Parellada M., Llorente C., Gonzalez-Peñas J., Carracedo A., Van Haeringen A., Ruivenkamp C., Nava C., Heron D., Nardello R., Iacomino M., Minetti C., Skabar A., Fabretto A., Hanna M.G., Bugiardini E., Hostettler I., O’Callaghan B., Khan A., Cortese A., O’Connor E., Yau W.Y., Bourinaris T., Kaiyrzhanov R., Chelban V., Madej M., Diana M.C., Vari M.S., Pedemonte M., Bruno C., Balagura G., Scala M., Fiorillo C., Nobili L., Malintan N.T., Zanetti M.N., Krishnakumar S.S., Lignani G., Jepson J.E.C., Broda P., Baldassari S., Rossi P., Fruscione F., Madia F., Traverso M., De-Marco P., Pérez-Dueñas B., Munell F., Kriouile Y., El-Khorassani M., Karashova B., Avdjieva D., Kathom H., Tincheva R., Van-Maldergem L., Nachbauer W., Boesch S., Gagliano A., Amadori E., Goraya J.S., Sultan T., Kirmani S., Ibrahim S., Jan F., Mine J., Banu S., Veggiotti P., Zuccotti G.V., Ferrari M.D., Van Den Maagdenberg A.M.J., Verrotti A., Marseglia G.L., Savasta S., Soler M.A., Scuderi C., Borgione E., Chimenz R., Gitto E., Dipasquale V., Sallemi A., Fusco M., Cuppari C., Cutrupi M.C., Ruggieri M., Cama A., Capra V., Mencacci N.E., Boles R., Gupta N., Kabra M., Papacostas S., Zamba-Papanicolaou E., Dardiotis E., Maqbool S., Rana N., Atawneh O., Lim S.Y., Shaikh F., Koutsis G., Breza M., Coviello D.A., Dauvilliers Y.A., AlKhawaja I., AlKhawaja M., Al-Mutairi F., Stojkovic T., Ferrucci V., Zollo M., Alkuraya F.S., Kinali M., Sherifa H., Benrhouma H., Turki I.B.Y., Tazir M., Obeid M., Bakhtadze S., Saadi N.W., Zaki M.S., Triki C.C., Benfenati F., Gustincich S., Kara M., Belcastro V., Specchio N., Capovilla G., Karimiani E.G., Salih A.M., Okubadejo N.U., Ojo O.O., Oshinaike O.O., Oguntunde O., Wahab K., Bello A.H., Abubakar S., Obiabo Y., Nwazor E., Ekenze O., Williams U., Iyagba A., Taiwo L., Komolafe M., Senkevich K., Shashkin C., Zharkynbekova N., Koneyev K., Manizha G., Isrofilov M., Guliyeva U., Salayev K., Khachatryan S., Rossi S., Silvestri G., Haridy N., Ramenghi L.A., Xiromerisiou G., David E., Aguennouz M., Fidani L., Spanaki C., Tucci A., Raspall-Chaure M., Chez M., Tsai A., Fassi E., Shinawi M., Constantino J.N., De Zorzi R., Fortuna S., Kok F., Keren B., Bonneau D., Choi M., Benzeev B., Zara F., Mefford H.C., Scheffer I.E., Clayton-Smith J., Macaya A., Rothman J.E., Eichler E.E., Kullmann D.M., Houlden H., SYNAPS Study Group (2019)
      AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at ...
    • Analysis of SOD2 rs4880 Genetic Variant in Patients with Alzheimer’s Disease 

      Siokas V., Stamati P., Pateraki G., Liampas I., Aloizou A.-M., Tsirelis D., Nousia A., Sgantzos M., Nasios G., Bogdanos D.P., Dardiotis E. (2022)
      A few gene loci that contribute to Alzheimer’s Disease (AD) onset have been identified. Few studies have been published about the relationship between SOD2 rs4880 single nucleotide variant and AD, revealing inconsistent ...
    • Anti-C1q autoantibodies are frequently detected in patients with systemic sclerosis associated with pulmonary fibrosis 

      Liaskos C., Rentouli S., Simopoulou T., Gkoutzourelas A., Norman G.L., Brotis A., Alexiou I., Katsiari C., Bogdanos D.P., Sakkas L.I. (2019)
      Background: Anti-C1q autoantibodies (autoAbs) are associated with systemic lupus erythematosus (SLE), but their presence in other rheumatic diseases has not been adequately investigated. Objectives: We aimed to assess ...
    • Anti-cd20 agents for multiple sclerosis: Spotlight on ocrelizumab and ofatumumab 

      Florou D., Katsara M., Feehan J., Dardiotis E., Apostolopoulos V. (2020)
      Until recently, in the pathogenesis of Multiple Sclerosis (MS), the contribution of B cells has been largely underestimated, and the disease was considered a T-cell-mediated disorder. However, newer evidence shows that B ...
    • Anti-Ro52 antibody is highly prevalent and a marker of better prognosis in patients with ovarian cancer 

      Bogdanos D.P., Gkoutzourelas A., Papadopoulos V., Liaskos C., Patrikiou E., Tsigalou C., Saratziotis A., Hajiioannou J., Scheper T., Meyer W., Sakkas L.I., Papandreou C. (2021)
      Background and Aims: Anti-Ro52 antibody (Ab) reactivity is highly prevalent in autoimmune rheumatic diseases (ARDs), mainly Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE), but also in other inflammatory ...
    • Antigen-specific humoral responses against Helicobacter pylori in patients with systemic sclerosis 

      Efthymiou G., Liaskos C., Simopoulou T., Marou E., Patrikiou E., Scheper T., Meyer W., Daoussis D., Sakkas L.I., Bogdanos D.P. (2020)
      Helicobacter pylori (Hp) is a likely trigger of systemic sclerosis (SSc), but systemic antigen-specific antibody (Ab) responses in a well-defined cohort of SSc patients have not been thoroughly assessed. Line immunoassay ...
    • Antihypertensive Medication Class and the Risk of Dementia and Cognitive Decline in Older Adults: A Secondary Analysis of the Prospective HELIAD Cohort 

      Liampas I., Hatzimanolis A., Siokas V., Yannakoulia M., Kosmidis M.H., Sakka P., Hadjigeorgiou G.M., Scarmeas N., Dardiotis E. (2022)
      Background: It is unclear whether the main antihypertensive medication classes (diuretics, calcium channel blockers, beta-blockers, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers (ARBs)) are ...
    • Antithrombotic Treatment Patterns of Patients with Symptomatic Peripheral Arterial Occlusive Disease in Germany: Evidence from Health Insurance Claims Data 

      Peters F., Kuchenbecker J., Acar L., Marschall U., L’Hoest H., Lareyre F., Spanos K., Behrendt C.-A. (2022)
      Objectives: Patients with peripheral arterial occlusive disease (PAOD) are at risk of worsening limb symptoms, major adverse cardiovascular events and exhibit an impaired life expectancy. There is a lack of evidence on the ...
    • Apocrine and eccrine hidrocystomas: A clinicopathological study 

      Koumaki D., Papadakis M., Lagoudaki E., Manios G.A., Kassotakis D., Doxastaki A., Krasagakis K., Manios A. (2021)
      Introduction: Eccrine and apocrine hidrocystomas are uncommon, benign, cystic proliferations of the sweat glands usually located on the head and neck area. Objectives: To describe the key clinical and histopathological ...
    • Apolipoprotein ϵ4 allele is associated with frailty syndrome: Results from the hellenic longitudinal investigation of ageing and diet study 

      Mourtzi N., Ntanasi E., Yannakoulia M., Kosmidis M., Anastasiou C., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N. (2019)
      Apolipoprotein (APOE) ϵ4 allele has been associated with a number of age-related diseases but previous studies failed to identify any link with Frailty syndrome. The aim of the present study is to investigate the association ...
    • Appetite control across the lifecourse: The acute impact of breakfast drink quantity and protein content. the full4health project 

      Crabtree D.R., Buosi W., Fyfe C.L., Horgan G.W., Manios Y., Androutsos O., Giannopoulou A., Finlayson G., Beaulieu K., Meek C.L., Holst J.J., Van Norren K., Mercer J.G., Johnstone A.M., Full4Health-Study Group (2020)
      Understanding the mechanisms of hunger, satiety and how nutrients affect appetite control is important for successful weight management across the lifecourse. The primary aim of this study was to describe acute appetite ...
    • Application of a home-based exercise program combined with tele-rehabilitation in previously hospitalized patients with COVID-19: A feasibility, single-cohort interventional study 

      Kortianou E.A., Tsimouris D., Mavronasou A., Lekkas S., Kazatzis N., Apostolara Z.E., Isakoglou M., Dimakou G., Barmparessou Z., Tsikrika S., Sakka V., Liontos A., Christaki M., Milionis H., Kalomenidis I. (2022)
      INTRODUCTION Telehealth for COVID-19 patients is still limited. We aimed to assess the clinical effects of a home-based tele-rehabilitation exercise program following hospital discharge during the first lockdown in Greece, ...